A compound found in black pepper that has been shown to enhance the absorption of certain nutrients and has potential benefits for digestion and metabolism. It increases 20 times the bioavailability of curcumin and significantly improves all benefits of curcumin.

A mineral that is important for the functioning of the immune system, taste perception, and wound healing. It can be found in foods such as oysters, beef, and beans. It is anti-viral (against e.g. SARS-CoV-2 virus), and can be used against cardiovascular diseases, affects the heart by modulating cardiomyocyte oxidative stress and maintaining myocardial structure, among other mechanisms.

An essential nutrient found in various foods such as carrots, sweet potatoes, and milk. It is important for maintaining healthy vision, skin, and immune function. It is anti-viral (against e.g. SARS-CoV-2 virus), and enhances the innate immune response against pathogens by acting on the major cellular subsets and inducing the release of pro-inflammatory cytokines and antimicrobial peptides, minimize the damage caused by the activation of the immune system against pathogens, reducing the oxidative damage, influencing the antigen presentation, enhancing the differentiation and proliferation of regulatory T cells, driving the differentiation of lymphocyte subsets, and modulating the production of pro-inflammatory cytokines.

A type of vitamin that the body can produce when exposed to sunlight, and is also found in certain foods such as fatty fish and mushrooms. It helps with calcium absorption and maintaining strong bones. It is anti-viral (against e.g. SARS-CoV-2 virus), anti-inflammatory, plays a major role regulating the immune system. Vitamin D3 deficiency may confer increased risk of influenza, respiratory tract infection and HIV infection. Vitamin D3 improves circulation and may prove to be beneficial in the treatment of hypertension and other cardiovascular diseases, including heart failure, myocardial infarction, vasculopathy, stroke and diabetes.

A type of vitamin found in animal-based foods such as meat, cheese, and eggs, as well as fermented foods like natto. It is important for blood clotting and bone health. Vitamin K2 and Magnesium should be supplemented together with Vitamin D3, in order to prevent long-term health-risk and improve immunoregulatory effects based on a causal loop diagram. Vitamin K2 is anticancer, antineoplastic, and together with vitamin D3 is beneficial for bone and cardiovascular health.

Magnesium is a mineral that is important for a variety of bodily functions, including maintaining strong bones, regulating heart rhythm, and supporting the immune system. Vitamin K2 and Magnesium should be supplemented together with Vitamin D3, in order to prevent long-term health-risk and improve immunoregulatory effects based on a causal loop diagram. Magnesium activates protein kinases, stimulates T-cell receptors and production by generating ATP, controls cell membrane inflammation, has vasodilatory and antithrombotic effects, and supresses the cytokine storm. It can be used against migraine headache, metabolic syndrome, diabetes, hyperlipidemia, asthma, premenstrual syndrome, preeclampsia, various cardiac arrhythmias, prevention of renal calculi and cataract formation, and as an adjunct or treatment for depression.